Research

Featured Study

Featured Study

ASTODRIMER SODIUM NASAL SPRAY VERSUS PLACEBO IN NON-HOSPITALISED PATIENTS WITH COVID-19: A RANDOMISED, DOUBLE-BLINDED, PLACEBO-CONTROLLED TRIAL

Our hero ingredient – Astodrimer Sodium – significantly reduced the viral load in older patients, particularly those aged 45 and above, leading to faster viral clearance and a quicker recovery, including from symptoms like loss of smell. 

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Peer-Reviewed Research

VIRALEZE™ contains astodrimer sodium, which has been shown in clinical and laboratory studies to trap and block cold and respiratory viruses. 

Explore some of the scientific publications here.

SCIENTIFIC REPORT

Virucidal and Antiviral Activity of Astodrimer Sodium Against SARS-CoV-2 in Vitro

Key Finding: Astodrimer Sodium demonstrated the ability to trap and block SARS-CoV-2 by over 99.9% within 1 minute of exposure, in laboratory studies.

SCIENTIFIC REPORT

Astodrimer Sodium Antiviral Nasal Spray for Reducing Respiratory Infections is Safe and Well Tolerated in a Randomized Controlled Trial

Key finding: Astodrimer Sodium 1% Nasal Spray was found to be safe and well-tolerated, with no systemic absorption and only mild, self-limiting side effects. The findings support its potential as a safe and innovative topical barrier nasal spray for reducing a broad spectrum of respiratory virus infections.

SCIENTIFIC REPORT

Astodrimer Sodium Nasal Spray Versus Placebo in Non-Hospitalised Patients with COVID-19: A Randomised, Double-Blinded, Placebo-Controlled Trial

Key Finding: Astodrimer Sodium significantly reduced the viral load in older patients, particularly those aged 45 and above, leading to faster viral clearance and a quicker recovery, including from symptoms like loss of smell.

SCIENTIFIC REPORT

Protective Effects of Astodrimer Sodium 1% Nasal Spray Formulation against SARS-CoV-2 Nasal Challenge in K18-hACE2 Mice

Key Finding: When SARS-CoV-2 was pre-treated with Astodrimer sodium, there was a 99% reduction in infectious virus in the lung and trachea of mice, showing strong preventative effects when applied before infection.

SCIENTIFIC REPORT

Nanotechnology-Based Strategies Against SARS-CoV-2 Variants

Key Finding: These findings support VIRALEZE™ as a scientifically validated, nanotechnology-based solution for respiratory virus protection, leveraging a physical rather than immune-based antiviral approach.

SCIENTIFIC REPORT

Astodrimer Sodium Nasal Spray Forms a Barrier to SARS-CoV-2 in Vitro and Preserves Normal Mucociliary Function in Human Nasal Epithelium

Key Finding: Astodrimer sodium nasal spray effectively reduced infectious viruses while preserving mucociliary function, showing a benign cytotoxicity profile in human nasal epithelium models. Compared to other nasal sprays, astodrimer sodium nasal spray demonstrated a superior ability to block virus.

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